Abstract: 【Objectives】 To analyze the changes in wetland landscape pattern in Zhalong National Nature Reserve, explore its landscape integrity and heterogeneity characteristics, evaluate the landscape dynamics of each functional area in combination with the functional zoning of Zhalong National Nature Reserve, and provide scientific references for wetland protection and management in Zhalong National Nature Reserve. 【Methods】 Based on the TM image data of Zhalong National Nature Reserve in 2008 and 2018, this study used ArcGIS10.2.2 software to analyze the spatial-temporal changes in the landscape pattern and count land use change and transfer. Fragstats 4.2 software was used to complete the calculation and analysis of each index. Combined with the field investigation, the conservation effectiveness of each functional area of Zhalong National Nature Reserve was evaluated from the landscape scale. 【Results】 The results showed that the patch quantity and patch density of moorlands in Zhalong National Nature Reserve decreased significantly from 2008 to 2018, the landscape aggregation degree increased, and the boundary density and separation decreased. Grassland, dryland, and saline-alkali land were the secondary components of Zhalong National Nature Reserve, and their patch number, patch density, and boundary density all decreased slightly, with the boundary separation showing an upward trend. The results of the landscape diversity index analysis showed that: with the landscape area unchanged, the number of landscapes in the nature reserve in 2018 was 762, and the patch density was 0.35, which was lower than the number of landscapes in 2008 (1 304 and the patch density was 0.60). From 2008 to 2018, the Shannon diversity index decreased from 1.38 to 1.32, the Shannon evenness index decreased from 0.6 to 0.57, and the contagion index of Zhalong Reserve increased from 66.55 to 68.33 from 2008 to 2018. From the perspective of the landscape area of each functional area of the reserve, the maximum area of the experimental zone was 78 142.59 hm², larger than the core zone (71 403.12 hm²) and the buffer zone (68 884.65 hm²). In terms of the number of landscapes, the maximum number of landscapes in the experimental zone waas 595, and the minimum number of landscapes in the core zone was 163. According to the patch density, the maximum patch density in the experimental zone was 0.76 (per 100 hm²). 【Conclusions】 The results showed that from 2008 to 2018, the landscape diversity index showed a downward trend, landscape integrity and connectivity showed an upward trend, landscape heterogeneity decreased, and patch types tended to be unitary in Zhalong Nature Reserve. The aggregation degree of the main landscape type (moorland) and the connectivity between patches increased, and the secondary fragmentation trend of patches and the connectivity decreased. In 2018, the landscape integrity of Zhalong National Nature Reserve ranked as core zone > buffer zone > experimental zone. The heterogeneity ranked as core zone < buffer zone < experimental zone. The landscape of the core zone was better than that of the buffer and experimental zones, indicating that the conservation effectiveness of the core zone was better than that of the buffer and experimental areas. Therefore, taking into account the local socio-economic conditions, it is recommended to further strengthen the protection of buffer zones and experimental areas and reduce human interference, to promote the balanced development of functional areas in reserves.