Abstract: Qianjiangyuan National Park pilot site (hereinafter referred to Qianjiangyuan National Park) is one of the 10 national park pilot sites in China. It collaborates with the Institute of Botany, Chinese Academy of Sciences and carries out researches on biodiversity protection and monitoring in Qianjiangyuan National Park. Through the establishment of five ecosystem and biodiversity monitoring and research platforms including forest dynamics plot monitoring platform, camera-trapping monitoring platform, forest canopy biodiversity monitoring platform, remote sensing monitoring platform, and environmental factors monitoring platform, a vertical integrated monitoring system has been formed to collect data to monitor the changes of ecosystems and plant and animal communities and to study the interactions among various ecological factors. A series of research results have been obtained, which provides a scientific basis for the management of Qianjiangyuan National Park. The case of biodiversity monitoring in Qianjiangyuan National Park has been included in the Report of Big Data for Sustainable Development Goals released by the Chinese government during the Session of the United Nations General Assembly in September 2019. The biodiversity monitoring system of Qianjiangyuan National Park can provide reference for the monitoring of biodiversity in other National Parks and natural reserve in China.